http://www.dictall.com/indu/374/3734101EF09.htm WebSep 17, 2015 · Coenzyme A (CoA) acts as the universal acyl carrier in metabolism, either directly or by providing the 4′-phosphopantetheine moiety of acyl and peptidyl carrier proteins 1, 2. It is ...
Phosphopantetheine - Wikipedia
WebWe demonstrate the fidelity of our model in recapitulating features of the human disease. Moreover, we identify pharmacodynamic biomarkers, provide insights into disease pathogenesis, and offer evidence for 4′-phosphopantetheine as a candidate therapeutic for PKAN. KW - 4′-phosphopantetheine. KW - NBIA. KW - PANK2. KW - PKAN. KW - coenzyme A Phosphopantetheine, also known as 4'-phosphopantetheine, is a prosthetic group of several acyl carrier proteins including the acyl carrier proteins (ACP) of fatty acid synthases, ACPs of polyketide synthases, the peptidyl carrier proteins (PCP), as well as aryl carrier proteins (ArCP) of nonribosomal peptide synthetases (NRPS). It is also present in formyltetrahydrofolate dehydrogenase. imt boynton beach
4’-磷酸泛酰巯基乙胺,4
WebAcyl carrier protein. The acyl carrier protein ( ACP) is a cofactor of both fatty acid and polyketide biosynthesis machinery. It is one of the most abundant proteins in cells of E. coli. [1] In both cases, the growing chain is bound to the ACP via a thioester derived from the distal thiol of a 4'- phosphopantetheine moiety. Webphosphopantetheine怎么翻译及发音. 沪江词库精选phosphopantetheine是什么意思、英语单词推荐. 磷酸泛酰巯基乙胺. 相似单词. phosphopantetheine 磷酸泛酰巯基乙胺. 最新单词. … WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs), also termed thiolation (T) domains’ – during the biosynthesis of fatty acids (FAs) (use ACPs) (Scheme 23), polyketides (PKs) (use ACPs) (Scheme 24), and … imt boynton