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The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein ... - PubMed

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IC50 - Wikipedia

WebbThe inhibition is covalent and allosteric and relies on an unusual stochastic mechanism. The mode of inhibition suggests that UCHL3 and K27Ub2 might be a stimulus-sensor … WebbIC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or … Webbbroad specificity for the inhibition of serine, cysteine, and metalloproteases. P2714 is supplied as a lyophilized powder. The inhibitors in P2714 are as follows, with … tops cnc heavy metal