WebJun 11, 2024 · Activation of JAK/STAT pathways leads to the induction of several hundred interferon-stimulated genes (ISGs) 14. The ISG products may directly limit viral replication 14,15,16; however, once again ... WebJan 20, 2024 · Gene expression profiling using DNA microarrays represents one of the earliest technologies for genomic high throughput analysis. About 20 years ago, this technique was used to characterize the abundance of transcripts of several thousand genes in subsets of normal B cells and DLBCL samples [].This comparison identified a group of …
The transcriptional regulator FUBP1 influences …
WebNov 9, 2024 · Background . Far upstream element-binding protein 1 (FUBP1) is reported to be involved in cancer development by regulating the transcription of c-myc gene through binding to far upstream element. Highly expressed FUBP1 was negatively correlated with survival rate of patients with hepatocellular carcinoma (HCC) and could promote the … WebJan 11, 2024 · The far upstream element (FUSE) binding protein 1 (FUBP1) is a single strand DNA and RNA binding factor that controls mRNA … heather stanton duncaster
TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor ... …
WebSep 1, 2024 · Although FUBP1 loss led to cell-type-specific AS of target genes, we observed that 8.5% of FUBP1-target genes are conserved among the AS events in both mammary epithelium and brain. This frequency is similar to the rate of FUBP1-target genes conserved between siFUBP1-U87MG cell line and primary glioma tumors with FUBP1 … WebOct 20, 2024 · The human FUBP1 gene spans 31,187 bp and displays two transcript variants (variant 1, NM_001303433 and variant 2, NM_003902) . The variant 1 is composed of 20 protein-coding exons and encodes a 655 amino acid protein, called the isoform 1. The variant 2 lacks an alternate in-frame exon in the 5′-coding region compared to variant 1, … WebFeb 27, 2015 · FUBP1 recruitment to the RNA sequence containing the ISE was established by RNA pull down and RNA EMSA, and further confirmed by RNA-ChIP on endogenous … movies for christian kids