WebAug 1, 2002 · Inactivation of CaTup1 or CaNrg1 causes C. albicans to grow in filamentous forms. These mutants are less virulent 32••., 33•., superficially suggesting that hyphal cells are less invasive than yeast cells. However, there may be trivial explanations for such observations. For example, hyperfilamentous microcolonies may not be disseminated ... WebHowever, CaMig1 and CaNrg1 repress other C. albicans genes in a CaTup1-independent fashion. The targets of CaMig1 and CaNrg1 repression, and phenotypic analyses of nrg1/nrg1 and mig1/mig1 mutants, indicate that these factors play differential roles in the regulation of metabolism, cellular morphogenesis and stress responses.
Inactivation or depletion of NRG1 derepresses ®lamentous …
WebAug 23, 2002 · We discovered that deletion ofCaNRG1 had no discernible effect on the iron-responsive regulation of CaARN1, whereas deletion of RFG1resulted in loss of … great movies to watch 2021
PRIME PubMed Differential expression of the NRG1 repressor …
WebNov 22, 2024 · Fts2 is not closely related in amino acid sequence to CaNrg1 and Rfg1, two major repressors of filamentation in C. albicans, yet it represses gene expression via the … WebCaNrg1 interacts specifically with an NRE in vitro. Also, deletion of two NREs from the ALS8 promoter releases it from Nrg1-mediated repression. Hence, CaNrg1 is a transcriptional repressor that appears to target CaTup1 to a distinct set of virulence-related functions, including yeast-hypha morphogenesis. PMID: 11532938 DOI full text PMC full text WebAlignment of the CaNrg1 C 2 H 2 domain (residues 226±286) from publication: EMBO J. 2001 Sep 3;20(17):4742-52. We have characterized CaNrg1 from Candida albicans, the major fungal pathogen in ... flood warnings and alerts