Web4. Conversion to Warfarin If the decision is made to continue anticoagulation with oral therapy (warfarin) after argatroban infusion, several steps should be taken to avoid the pro-thrombotic effects of warfarin: o Do not use warfarin as monotherapy in acute HIT o Do not initiate warfarin until the platelet count has rebounded to >100 K/µL Webuninterrupted warfarin (16% vs. 3.5%; p < 0.001). Strokes and transient ischemic attacks occurred in 2 patients on uninterrupted warfarin (0.3%), with no statistically significant difference between the groups. Nevertheless, in many circumstances, interruption of chronic anticoagulation will be necessary to avoid
CLEVELAND CLINIC ANTICOAGULATION MANAGEMENT …
Web&rs\uljkw 7kh 8qlyhuvlw\ ri 7h[dv 0' $qghuvrq &dqfhu &hqwhu $33(1',; & 1rq khsdulq $qwlfrdjxodqwv 'rvlqj dqg 0rqlwrulqj 'uxj'rvlqj 'rvh $gmxvwphqwv &rqvlghudwlrqv WebSep 1, 2009 · Transition from bivalirudin, a direct thrombin inhibitor (DTI), to warfarin resulted in extensive re-thrombosis, and fondaparinux therapy similarly failed. She was then treated with argatroban, and transitioned successfully to warfarin after nine weeks. burgee \u0026 abramoff pc
UW Medicine Anticoagulation Services - University of Washington
WebBivalirudin may cause a falsely prolonged international normalized ratio (INR) that complicates the discontinuation of bivalirudin when used as a bridge to warfarin. WebMay 1, 2024 · After bivalirudin discontinuation, 68% of patients had a therapeutic INR. The results of this prospective analysis successfully validated our novel bivalirudin to … WebBackground: Transition from bivalirudin to long-term warfarin therapy is often difficult to execute due to bivalirudin prolongation of the international normalized ratio (INR), and … burge engineering \\u0026 associates